Pharmaceutical care improves medication adherence and quality of life in type 2 diabetes mellitus

Pharmacy Practice

  • Angélica Marchesi Lira-Meriguete1Graduate Program in Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, Brazil.
  • Mayara Paes Santos1Graduate Program in Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, Brazil.
  • Viviam Cerqueira de Souza Viana2Graduate Program in Pharmaceutical Services, University of Vila Velha, Espírito Santo, Brazil.
  • Nadmy Arrivabene Zavaris Gonçalves3Graduate Program in Biochemistry and Pharmacology, Federal University of Espírito Santo, Vitória, Brazil.
  • Francine Costa Guimarães1Graduate Program in Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, Brazil.
  • Lorena Rocha Ayres4Department of Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, Brazil.
  • Daniela Amorim Melgaço Guimarães do Bem1Graduate Program in Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, Brazil., 4Department of Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, Brazil.
  • Rita de Cássia Ribeiro Gonçalves1Graduate Program in Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, Brazil., 4Department of Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, Brazil.

Volume 21 Issue 4 Pages 1-7

DOI: 10.18549/PharmPract.2023.4.2869

Abstract

Aims: This study aimed to evaluate whether pharmacotherapeutic follow-up in patients with T2DM in primary care interferes in metabolic control, cardiovascular risk, medication adherence and quality of life. Methods: A prospective clinical study was conducted at two Primary Health Units in Vitória, Espírito Santo, Brazil with 75 patients with T2DM between 40 and 70 years old. The parameters of metabolic control evaluated included fasting blood glucose, HbA1c, triglyceride/HDL-c and total cholesterol/HDL-c ratio. The cardiovascular risk was calculated based on the Framingham risk score. Adherence to medication was measured using the Brief Medication Questionnaire and quality of life was evaluated by applying the World Health Organization Quality of Life-Bref. Results: After the follow-up, there was a significant decreasing in cardiovascular risk (p=0.048) and total cholesterol/HDL-c ratio (p=0.024) and a discrete improvement in fast glucose and HbA1c levels. The quality of life scores increased for all domains (p<0.0001) and the treatment adherence also improved with 12.00% of the patients classified as low adherence in the final time, against 41.33% before the meetings. Conclusion: These results show the proposed pharmacotherapeutic follow-up influenced positively cardiovascular risk, adherence to therapy and quality of life in all domains, and, therefore, may contribute to delay the onset of the main chronic complications of the disease.

Keywords

  • Pharmaceutical care
  • cardiovascular risk
  • medication adherence
  • quality of life
Pharmacy Practice

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