Evaluation of the value of ChatGPT as a self-medication patients’ advisor for minor ailments in comparison with community pharmacist: A Cross-sectional study

Pharmacy Practice

  • Sham ZainAlabdin1BCPS, MSc. Clinical Pharmacy, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, UAE University, Al-Ain, UAE.
  • Alya Ayeh2MD, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, UAE University, Al-Ain, UAE.
  • Aahad AlAli2MD, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, UAE University, Al-Ain, UAE.
  • Maryam Alfadli2MD, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, UAE University, Al-Ain, UAE.
  • Fatma AlMarzooqi2MD, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, UAE University, Al-Ain, UAE.
  • Sara AlDhaheri2MD, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, UAE University, Al-Ain, UAE.
  • Noor AlAreqi3PharmD, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, UAE University, Al-Ain, UAE.
  • Nazar Zaki4PhD, Professor, Department of Computer Science and Software Engineering, College of Information Technology, United Arab Emirates University, Al Ain, United Arab Emirates.
  • Mosab Arafat5PhD, Professor, College of Pharmacy, Al Ain University, Al Ain, UAE.
  • Amal Akour6PhD, Associate Professor, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, UAE University, Al-Ain, UAE., 7Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Amman, Jordan.
  • Salah Aburuz8PhD, Professor, Department of Pharmacology and Therapeutics, College of Medicine & Health Sciences, UAE University, Al-Ain, UAE.

Volume 24 Issue 2 Pages 1-10

DOI: 10.18549/PharmPract.2026.2.3448

Abstract

The Objectives: This study aims to evaluate the value of ChatGPT in helping patients select appropriate self-care and over-the-counter medications for minor ailments compared to community pharmacists (CP).Method: The study used a cross-sectional assessment and a covert simulated patient study, in which three clinical pharmacists prepared 91 clinical scenarios representing the most common OTC indications. These case scenarios were presented to ChatGPT and community pharmacists to compare generated responses in several aspects. Accuracy, patient-centeredness, comprehensiveness, and word count of responses from both ChatGPT and community pharmacists were assessed by three clinical pharmacists.Results: It was found that ChatGPT responses were more accurate (4.51±0.64 vs 3.78±0.89), patient-centered (4.46±0.70 vs 3.68±0.88), and comprehensive (4.38±0.71 vs 2.68±1.26) compared to pharmacists’ responses (p<0.001). Cosine similarity showed that the majority (40.7%, n=37) of cases answered by community pharmacists were moderately like that of ChatGPT, with an average score of 0.51±0.23.Conclusion: The study suggests ChatGPT is an accurate tool for a self-medication advisor for minor ailments. It is important to emphasize that this tool should be used to support patients and pharmacists rather than being the sole source of drug information, as therapy individualization and up-to-date information can’t be achieved without pharmacists’ intervention. It also underscores the need for enhancing pharmacists’ and pharmacy students’ training in minor ailments recommendations and management.

Keywords

  • ChatGPT
  • Community Pharmacist
  • Self-medication
  • Minor ailments
  • Artificial intelligence in healthcare
Pharmacy Practice

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