The incidence and factors affecting post-caesarean surgical site infections at a private hospital: A prospective cohort study

Pharmacy Practice

  • Munther S. Alnajjar1College of Pharmacy, American University of Iraq-Baghdad, IRAQ.
  • Dima Saeed2Department of Pharmacology & Clinical Pharmacy, School of Pharmacy, Middle East University, Amman, JORDAN.
  • Lilian Alnsour3Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UNITED ARAB EMIRATES.
  • Ola Harbi Abdallah4Department of Pharmacy, Istishari Hospital, Amman, JORDAN.
  • Sami Ali Qadus5Applied and Clinical Pharmacy Department, Faculty of Pharmacy, Isra University, Amman, JORDAN.
  • Islam A. Berdaweel6Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Yarmouk University, Irbid 22110, JORDAN.
  • Nagham Abdulsattar1College of Pharmacy, American University of Iraq-Baghdad, IRAQ.

Volume 24 Issue 3 Pages 1-10

DOI: 10.18549/PharmPract.2026.3.3575

Abstract

Aim/Background: One-third of all births in Jordan are done by caesarean section, which is almost double the global recommended rate. This continuous increase in caesarean delivery rates has contributed to an increase in surgical site infection (SSI) rate. Objectives: To assess the rate of surgical site infection (SSI) after elective caesarean deliveries. Also, we explored the predisposing factors that are associated with these infections. Design: we conducted a prospective observational cohort study at Istishari Hospital (IH), a major tertiary hospital in Jordan. Materials and Methods: A total of 184 women underwent caesarean deliveries between October 2021, and September 2022 were included, and SSI was identified both during the hospital stay and within 30 days after the discharge. Results: during the 1-year study period, post-caesarean SSI was detected in 6 (3.3%) of 184 women who underwent caesarean operations. A multivariable logistic regression analysis showed that diabetic women have significantly higher post-caesarean SSI risk compared to their non-diabetic counterpart (OR, 28.7 [95% CI, 2.1-404.2]), (P=0.013). Conclusion: Having diabetes was found as an independent predictor of post-caesarean SSI, suggesting that tailored antibiotic prophylaxis may be beneficial for this population. Incorporating diabetes as key risk factor in post-caesarean SSI prevention strategies is essential prevention strategy in improving caesarean patient’s outcomes.

Keywords

  • Caesarean section
  • Surgical site infections (SSIs)
  • Caesarean infections
  • Cohort study
Pharmacy Practice

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